July 2008
Three new drugs for type 2 diabetes
For many patients with type 2 diabetes mellitus, metformin plus appropriate treatment for cardiovascular risk factors form the cornerstone of drug therapy. Three drugs in two new classes that act on the hormonal regulation of insulin secretion have been launched recently for use as add-in therapies in patients with type 2 diabetes - this article considers whether they have a role in the management of such individuals.Update on managing Bell's palsy
There has been longstanding controversy about what, if any, treatment should be given for Bell’s palsy. This article reconsiders advice given in our article Managing Bell's palsy in the light of recently published evidence.Tests for equivalence or non-inferiority - why?
Drugs are sometimes assessed in clinical trials designed to test their equivalence or non-inferiority to a standard therapy. This article summarises the main features of equivalence and non-inferiority trials and suggests what to look out for when reading study reports.Free trial
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